WEKO3
アイテム
{"_buckets": {"deposit": "3520c764-d461-46fc-b017-9043be123bf2"}, "_deposit": {"created_by": 16, "id": "1041", "owners": [16], "pid": {"revision_id": 0, "type": "depid", "value": "1041"}, "status": "published"}, "_oai": {"id": "oai:phoenix.repo.nii.ac.jp:00001041", "sets": ["44"]}, "author_link": ["489", "488", "7", "9", "483", "11", "476", "477", "482"], "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-03", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "9", "bibliographicPageStart": "5", "bibliographicVolumeNumber": "3", "bibliographic_titles": [{"bibliographic_title": "九州保健福祉大学研究紀要"}, {"bibliographic_title": "Journal of Kyushu University of Health and Welfare", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "池脇, 信直", "creatorNameLang": "ja"}, {"creatorName": "イケワキ, ノブナオ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Ikewaki, Nobunao", "creatorNameLang": "en"}], "familyNames": [{"familyName": "池脇", "familyNameLang": "ja"}, {"familyName": "イケワキ", "familyNameLang": "ja-Kana"}, {"familyName": "Ikewaki", "familyNameLang": "en"}], "givenNames": [{"givenName": "信直", "givenNameLang": "ja"}, {"givenName": "ノブナオ", "givenNameLang": "ja-Kana"}, {"givenName": "Nobunao", "givenNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002154389", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002154389"}, {"nameIdentifier": "1000090193226", "nameIdentifierScheme": "NRID"}, {"nameIdentifier": "90193226", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90193226"}]}, {"creatorNames": [{"creatorName": "藤井, 昇"}, {"creatorName": "フジイ, ノボル", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "476", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052222", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052222"}]}, {"creatorNames": [{"creatorName": "尾仲, 隆"}, {"creatorName": "オナカ, タカシ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "477", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052223", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052223"}]}]}, "item_1_creator_7": {"attribute_name": "著者名よみ", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "イケワキ, ノブナオ"}], "nameIdentifiers": [{"nameIdentifier": "9", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002154389", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002154389"}]}, {"creatorNames": [{"creatorName": "フジイ, ノボル"}], "nameIdentifiers": [{"nameIdentifier": "482", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052222", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052222"}]}, {"creatorNames": [{"creatorName": "オナカ, タカシ"}], "nameIdentifiers": [{"nameIdentifier": "483", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052223", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052223"}]}]}, "item_1_creator_8": {"attribute_name": "著者名(英)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "IKEWAKI, Nobunao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "11", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002154389", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002154389"}]}, {"creatorNames": [{"creatorName": "FUJII, Noboru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "488", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052222", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052222"}]}, {"creatorNames": [{"creatorName": "ONAKA, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "489", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000006052223", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000006052223"}]}]}, "item_1_description_1": {"attribute_name": "ページ属性", "attribute_value_mlt": [{"subitem_description": "Q(文献目録など)", "subitem_description_type": "Other"}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "我々はAureobasidium pullulans FERM-P4257から産生される多糖の分離精製に成功した。今回、この多糖の生体免疫反応に与える影響を検討したところ、この多糖が細菌の貪食に密接に関与するCD11b抗原の発現を増強させること、また、免疫系ネットワークの調節に関わるインターロイキン8(IL 8)の産生を有意に誘導することを見い出した。この結果はAureobasidium pullulans FERM-P4257から産生される多糖に生体免疫反応を調節する作用があることを示すものである。", "subitem_description_type": "Other"}]}, "item_1_description_12": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "We previously succeeded in purifying a polysaccharide containing β-1.3-1.6 glucan produced by the yeast Aureobasidium pullulans FERM-P4257. In this study we investigated immunological regulation by this polysaccharide at the cellular level in human monocyte-like cell line U937. The percentage of positive cells and the mean fluorescence intensity (MFI) of CD11b antigen on the U937 cells were significantly up-regulated, and the cells morphologically altered by culture with the polysaccharide for 96 hr. On the other hand, the U937 cells cultured with the polysaccharide were found to produce interleukin-8 (IL-8) at 24 and 48 hr according to the results of an enzyme immunoassay (EIA), and the differences between the presence and absence of the polysaccharide were significant (P=0.0029 and P=0.0016, respectively). These findings indicate that a polysaccharide produced by Aureobasidium pullulans FERM-P4257 significantly up-regulated human immune responses.", "subitem_description_type": "Other"}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11490417", "subitem_source_identifier_type": "NCID"}]}, "item_1_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Occupational Therapy, School of Health Science, Kyushu University of Health and Welfare"}, {"subitem_text_language": "en", "subitem_text_value": "Seishin Ursura Gakuen Mission Junior College"}, {"subitem_text_language": "en", "subitem_text_value": "Sophy Incorporation"}]}, "item_1_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "九州保健福祉大学保健科学部作業療法学科"}, {"subitem_text_value": "聖心ウルスラ学園短期大学食物栄養学科"}, {"subitem_text_value": "株式会社ソフィ"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Aureobasidium pullulans FERM-P4257", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CD11b抗原", "subitem_subject_scheme": "Other"}, {"subitem_subject": "免疫反応", "subitem_subject_scheme": "Other"}, {"subitem_subject": "インターロイキン8", "subitem_subject_scheme": "Other"}, {"subitem_subject": "U937細胞", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Aureobasidium pullulans FERM-P4257", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CD11b antigen", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "immune response", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "interleukin 8", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "U937 cells", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Aureobasidium pululans FERM-P4257由来の多糖によるCD11b抗原の発現増強とインターロイキン8(IL-8)の産生", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Aureobasidium pululans FERM-P4257由来の多糖によるCD11b抗原の発現増強とインターロイキン8(IL-8)の産生"}, {"subitem_title": "A polysaccharide produced by Aureobasidium pululans FERM-P4257 up-regulates expression of CD11b antigen and induces interleukin-8(IL-8) production", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "16", "path": ["44"], "permalink_uri": "https://phoenix.repo.nii.ac.jp/records/1041", "pubdate": {"attribute_name": "公開日", "attribute_value": "2002-03-01"}, "publish_date": "2002-03-01", "publish_status": "0", "recid": "1041", "relation": {}, "relation_version_is_last": true, "title": ["Aureobasidium pululans FERM-P4257由来の多糖によるCD11b抗原の発現増強とインターロイキン8(IL-8)の産生"], "weko_shared_id": -1}
Aureobasidium pululans FERM-P4257由来の多糖によるCD11b抗原の発現増強とインターロイキン8(IL-8)の産生
https://phoenix.repo.nii.ac.jp/records/1041
https://phoenix.repo.nii.ac.jp/records/10418a560611-8dc1-44a8-aed4-265902bdf893
Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2002-03-01 | |||||||||||
タイトル | ||||||||||||
タイトル | Aureobasidium pululans FERM-P4257由来の多糖によるCD11b抗原の発現増強とインターロイキン8(IL-8)の産生 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | A polysaccharide produced by Aureobasidium pululans FERM-P4257 up-regulates expression of CD11b antigen and induces interleukin-8(IL-8) production | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | Aureobasidium pullulans FERM-P4257 | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | CD11b抗原 | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | 免疫反応 | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | インターロイキン8 | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | U937細胞 | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Aureobasidium pullulans FERM-P4257 | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | CD11b antigen | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | immune response | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | interleukin 8 | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | U937 cells | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | departmental bulletin paper | |||||||||||
アクセス権 | ||||||||||||
アクセス権 | metadata only access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||||
ページ属性 | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | Q(文献目録など) | |||||||||||
著者名(日) |
池脇, 信直
× 池脇, 信直
WEKO
7
× 藤井, 昇× 尾仲, 隆 |
|||||||||||
著者名よみ |
イケワキ, ノブナオ
× イケワキ, ノブナオ× フジイ, ノボル× オナカ, タカシ |
|||||||||||
著者名(英) |
IKEWAKI, Nobunao
× IKEWAKI, Nobunao× FUJII, Noboru× ONAKA, Takashi |
|||||||||||
著者所属(日) | ||||||||||||
九州保健福祉大学保健科学部作業療法学科 | ||||||||||||
著者所属(日) | ||||||||||||
聖心ウルスラ学園短期大学食物栄養学科 | ||||||||||||
著者所属(日) | ||||||||||||
株式会社ソフィ | ||||||||||||
著者所属(英) | ||||||||||||
en | ||||||||||||
Department of Occupational Therapy, School of Health Science, Kyushu University of Health and Welfare | ||||||||||||
著者所属(英) | ||||||||||||
en | ||||||||||||
Seishin Ursura Gakuen Mission Junior College | ||||||||||||
著者所属(英) | ||||||||||||
en | ||||||||||||
Sophy Incorporation | ||||||||||||
抄録(日) | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | 我々はAureobasidium pullulans FERM-P4257から産生される多糖の分離精製に成功した。今回、この多糖の生体免疫反応に与える影響を検討したところ、この多糖が細菌の貪食に密接に関与するCD11b抗原の発現を増強させること、また、免疫系ネットワークの調節に関わるインターロイキン8(IL 8)の産生を有意に誘導することを見い出した。この結果はAureobasidium pullulans FERM-P4257から産生される多糖に生体免疫反応を調節する作用があることを示すものである。 | |||||||||||
抄録(英) | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | We previously succeeded in purifying a polysaccharide containing β-1.3-1.6 glucan produced by the yeast Aureobasidium pullulans FERM-P4257. In this study we investigated immunological regulation by this polysaccharide at the cellular level in human monocyte-like cell line U937. The percentage of positive cells and the mean fluorescence intensity (MFI) of CD11b antigen on the U937 cells were significantly up-regulated, and the cells morphologically altered by culture with the polysaccharide for 96 hr. On the other hand, the U937 cells cultured with the polysaccharide were found to produce interleukin-8 (IL-8) at 24 and 48 hr according to the results of an enzyme immunoassay (EIA), and the differences between the presence and absence of the polysaccharide were significant (P=0.0029 and P=0.0016, respectively). These findings indicate that a polysaccharide produced by Aureobasidium pullulans FERM-P4257 significantly up-regulated human immune responses. | |||||||||||
雑誌書誌ID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AA11490417 | |||||||||||
書誌情報 |
九州保健福祉大学研究紀要 en : Journal of Kyushu University of Health and Welfare 巻 3, p. 5-9, 発行日 2002-03 |