{"created":"2023-06-19T08:50:59.119323+00:00","id":1306,"links":{},"metadata":{"_buckets":{"deposit":"a26b94e1-ba78-4950-adda-4111db0995b1"},"_deposit":{"created_by":16,"id":"1306","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"1306"},"status":"published"},"_oai":{"id":"oai:phoenix.repo.nii.ac.jp:00001306","sets":["35:104"]},"author_link":["7","11","7302","811","7656"],"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"18","bibliographicPageEnd":"72","bibliographicPageStart":"67","bibliographic_titles":[{"bibliographic_title":"九州保健福祉大学研究紀要 = Journal of Kyushu University of Health and Welfare"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"池脇, 信直","creatorNameLang":"ja"},{"creatorName":"イケワキ, ノブナオ","creatorNameLang":"ja-Kana"},{"creatorName":"Ikewaki, Nobunao","creatorNameLang":"en"}],"familyNames":[{"familyName":"池脇","familyNameLang":"ja"},{"familyName":"イケワキ","familyNameLang":"ja-Kana"},{"familyName":"Ikewaki","familyNameLang":"en"}],"givenNames":[{"givenName":"信直","givenNameLang":"ja"},{"givenName":"ノブナオ","givenNameLang":"ja-Kana"},{"givenName":"Nobunao","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000002154389","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000002154389"},{"nameIdentifier":"1000090193226","nameIdentifierScheme":"NRID"},{"nameIdentifier":"90193226","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90193226"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"園田, 徹","creatorNameLang":"ja"},{"creatorName":"ソノダ, トオル","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"園田","familyNameLang":"ja"},{"familyName":"ソノダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"徹","givenNameLang":"ja"},{"givenName":"トオル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"811","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000004394692","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000004394692"},{"nameIdentifier":"1000070187897","nameIdentifierScheme":"NRID"},{"nameIdentifier":"70187897","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70187897"}]},{"creatorNames":[{"creatorName":"東, 和弘"},{"creatorName":"アズマ, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"7302","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000293527533","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000293527533"}]}]},"item_1_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"いけわき, のぶなお"}],"nameIdentifiers":[{"nameIdentifier":"7656","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"IKEWAKI, Nobunao","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"11","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000002154389","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000002154389"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"スイソニアから発生する水素ガス（濃度0.1～0.3％）を含む蒸気混合ガス“XEN”を鼻カニューラで吸入した。吸入後、唾液中の免疫バイオマーカーの動態を酵素抗体法（enzyme immunoassay：EIA）で解析した。その結果、“XEN”吸入15分後、唾液中のインターロイキン-1β（IL-1β）の濃度が吸入前と比較して有意に増加した（P<0.01）。一方、唾液中の可溶性CD44分子（sCD44）は吸入前後で有意な差は認められなかった。以上の結果は、“XEN”が鼻粘膜免疫系を活性化し、生体の免疫力を増強させる作用があることを示唆するものである。","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"In this preliminary study, we examined the effects of inhalation of a steam mixed gas containing\nhydrogen gas on the salivary levels of immune biomarkers, especially interleukin-1????and soluble-form\nCD44, in healthy adult volunteers. This gas was generated by the decomposition of superheated steam\nusing a machine (Suisonia) manufactured by Earth Engineering Co., and was designated as“XEN”in our\nlaboratory. The salivary levels of interleukin-1????and soluble-form CD44 were measured by enzyme\nimmunoassay 15 min after the subjects had inhaled “XEN” via a nasal cannula. The results revealed a\nsignificant increase in salivary interleukin-1????levels (P < 0.01), but no significant change (P = 0.093) in\nsalivary soluble-form CD44 levels at 15 min after“XEN”inhalation, compared to the values measured\nbefore inhalation. These findings indicate that “XEN”rapidly induces salivary interleukin-1????secretion and\nthat elevated salivary interleukin-1????levels after“XEN”inhalation may reflect the activation of both\nnatural and acquired immune responses in the living body.","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11490417","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Medical Life Science, Kyushu University of Health and Welfare School of Medical Life Science, Institute of Immunology,"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"九州保健福祉大学生命医科学部生命医科学科・順正学園免疫学研究所"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-07-24"}],"displaytype":"simple","filename":"67-72水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析.pdf","filesize":[{"value":"338.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"67-72水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析","url":"https://phoenix.repo.nii.ac.jp/record/1306/files/67-72水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析.pdf"},"version_id":"9b4c7867-2ab4-4bf6-b6de-787496620b0c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"インターロイキン1β","subitem_subject_scheme":"Other"},{"subitem_subject":"唾液バイオマーカー","subitem_subject_scheme":"Other"},{"subitem_subject":"可溶性CD44","subitem_subject_scheme":"Other"},{"subitem_subject":"水素ガス含有蒸気混合ガス","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-1β,salivary immune biomarker","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sCD44","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"steam mixed gas containing hydrogen gas","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"XEN","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析"},{"subitem_title":"Analysis of the salivary levels of immune biomarkers after inhalation of a steam mixed gas containing hydrogen gas","subitem_title_language":"en"}]},"item_type_id":"1","owner":"16","path":["104"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-07-24"},"publish_date":"2017-07-24","publish_status":"0","recid":"1306","relation_version_is_last":true,"title":["水素ガスを含む蒸気混合ガス吸入後の唾液バイオマーカーの解析"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2024-04-19T06:59:45.926689+00:00"}