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Hidekazu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"492","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000003520421","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000003520421"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"我々は, β-1.3-1.6グルカンが免疫系の調節に密接に関わるインターロイキン8 (IL-8) の産生を誘導することを見出し, 本誌 (3 : 5～9, 2002) に報告した. 今回は, β-1.3-1.6グルカンをマウスに免疫して得られた腹膜腔内浮遊細胞の特徴について検討したところ, 細胞数の増加, 形態変化, さらにはNK活性 (抗腫瘍作用) の上昇が認められた. また, two-color flow cytometry 法からNK活性を獲得した細胞は, Mac-1+NK1.1+の細胞群であることも判明した. この結果は, β-1.3-1.6グルカンがマウス腹膜腔内浮遊細胞に対して免疫能を付与したことを示すものである.","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"We previously succeeded in purifying β-1.3-1.6 glucan produced by the black yeast Aureobasidium pullulans, and reported that this β-1.3-1.6 glucan has unique immunological actions such as inducement of CD11b antigen expression and interleukin-8 (IL-8) production in the human monocyte like cell line, U937. In this study, we investigated some immunological properties of mouse peritoneal cells immunized withβ-1.3-1.6 glucan. The peritoneal cell number immunized with β-1.3-1.6 glucan was significantly enhanced accompanied by morphological changes (spread formation). Furthermore, the peritoneal cells immunized with β-1.3-1.6 glucan acquired natural killer (NK) activity against YAC-1 lymphoma cells. In addition, it was found that double positive cells expressing both Mac-1 (macrophage specific antigen) and NK1.1 (natural killer cell specific antigen) on the peritoneal cells immunized with β-1.3-1.6 glucan were significantly enhanced using two-color flow cytometric analysis. These findings indicate that peritoneal cells immunized with β-1.3-1.6 glucan produced by Aureobasidium pullulans sufficiently acquired immunological activities.","subitem_description_type":"Other"}]},"item_1_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15069/00000539","subitem_identifier_reg_type":"JaLC"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11490417","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of occupational therapy, School of health and science, Kyushu University of Health and Welfare"},{"subitem_text_language":"en","subitem_text_value":"Seishin Ursura Gakuen Mission Junior College"},{"subitem_text_language":"en","subitem_text_value":"Sophy Corporation"},{"subitem_text_language":"en","subitem_text_value":"Department of occupational therapy, School of health and science, Kyushu University of Health and Welfare"},{"subitem_text_language":"en","subitem_text_value":"Department of occupational therapy, School of health and science, Kyushu University of Health and Welfare"},{"subitem_text_language":"en","subitem_text_value":"Department of microbiology, Kitasato Uiversity School of Medicine"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"九州保健福祉大学保健科学部作業療法学科"},{"subitem_text_value":"聖心ウルスラ学園短期大学食物栄養学科"},{"subitem_text_value":"ソフィ株式会社"},{"subitem_text_value":"九州保健福祉大学保健科学部作業療法学科"},{"subitem_text_value":"九州保健福祉大学保健科学部作業療法学科"},{"subitem_text_value":"北里大学医学部微生物学"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2004-03-25"}],"displaytype":"simple","filename":"KJ00004256806.pdf","filesize":[{"value":"739.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"KJ00004256806","url":"https://phoenix.repo.nii.ac.jp/record/541/files/KJ00004256806.pdf"},"version_id":"9e034b01-af1f-4adf-9967-3ed98edf33ee"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Aureobasidium pullulans","subitem_subject_scheme":"Other"},{"subitem_subject":"β-1.3-1.6グルカン","subitem_subject_scheme":"Other"},{"subitem_subject":"NK活性","subitem_subject_scheme":"Other"},{"subitem_subject":"腹膜腔内浮遊細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"Aureobasidium pullulans","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"β-1.3-1.6 glucan","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"NK activity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"peritoneal cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Aureobasidium pullulans の産生するβ-1.3-1.6グルカンを免疫して得られマウス腹膜腔内浮遊細胞の特徴","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Aureobasidium pullulans の産生するβ-1.3-1.6グルカンを免疫して得られマウス腹膜腔内浮遊細胞の特徴"},{"subitem_title":"Properties of the mouse peritoneal cells immunized with β-1.3-1.6 glucan produced by Aureobasidium pullulans","subitem_title_language":"en"}]},"item_type_id":"1","owner":"16","path":["47"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-03-25"},"publish_date":"2004-03-25","publish_status":"0","recid":"541","relation_version_is_last":true,"title":["Aureobasidium pullulans の産生するβ-1.3-1.6グルカンを免疫して得られマウス腹膜腔内浮遊細胞の特徴"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2024-04-19T06:59:44.148632+00:00"}